欧阳玮

姓名

欧阳玮  

性别

出生年月

1968.5

籍贯

湖南

电子照片

职称

校聘教授

职务


学历

博士

学位

博士

研究方向

运动性相关的脑创伤及骨骼肌损伤


导师类别

运动人体科学、体育教学、运动训练


通讯地址

浙江省金华市婺城区迎宾大道688号浙师大万博体育充值方式

邮编

321004


联系电话

0579-82291009

E-mail

wouyang@zjnu.cn


一、个人简历

浙江师范大学2013年度引进人才,校聘教授。2000年于复旦大学医学神经生物国家重点实验室获得神经生物学博士学位。20002007年在美国康奈尔大学医学院麻醉系做博士后和研究员,从事麻醉剂在神经系统的机制研究,对于疼痛中枢机制、出血性中风及麻醉剂中枢机制均有出色研究。目前主要从事运动性相关的脑创伤及骨骼肌损伤机制研究,截止2018年发表SCI论文30余篇。


二、主要成果介绍:(著作 论文 课题 获奖等)

论文:

Modified device for fluid percussion injury in rodents. Journal of Neuroscience Research J Neuro Res. 2018;00:1–18.

Effect of fluoride exposure on mRNA expression of cav1.2 and calcium signal pathway apoptosis regulators in PC12 cells. Environ Toxicol Pharmacol. 2017 Sep;54:74-79.

Effects of Different Levels of Calcium Intake on Brain Cell Apoptosis in Fluorosis Rat Offspring and Its Molecular Mechanism. Biol Trace Elem Res. 2017 Apr;176(2):355-366.

The molecular mechanisms of the renal injury in fluorosis induced by drinking water with a high fluoride ion content and the effects of selenium intervention. Fluoride. 2017 50(1 Pt 2)105–120

Moderate injury in motor-sensory cortex causes behavioral deficits accompanied by electrophysiological changes in mice adulthood. PLoS One. 2017 Feb 14;12(2):e0171976.   

Effects of Sodium Fluoride on Lipid Peroxidation and PARP, XBP-1 Expression in PC12 Cell. Biol Trace Elem Res. 2016 Sep;173(1):161-7.

Molecular mechanism of brain impairment caused by drinking-acquired fluorosis and selenium intervention. Environ Toxicol Pharmacol. 2016 Apr;43:134-9.  

Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane. Br J Anaesth. 2015 Jul;115(1):112-21.   

Dynamic   monitoring of beating periodicity of stem cell-derived cardiomyocytes as a   predictive tool for preclinical safety assessment. Br J Pharmacol. 2012, 165:   1424–1441.

Effects of   Halogenated Inhaled Anesthetics on Voltage-gated Na+ Channel Function. Anesthesiology 2009, 110:582-590.

Inhibits Tetrodotoxin-resistant Voltage-gated Sodium Channel Nav1.8.  Anesthesiology   2009, 111:591-599.

Isoflurane   inhibits NaChBac, a prokaryotic voltage-gated sodium channel. J Pharmacol Exp Ther 2007, 322:1076-1083.

Isoform-selective   effects of isoflurane on voltage-gated Na+ channels. Anesthesiology 2007, 107:91-98.

Depression by   isoflurane of the action potential and underlying voltage-gated ion currents   in isolated rat neurohypophysial nerve terminals. J Pharmacol Exp Ther. 2005, 312:801-808.

Distinct rat   neurohypophysial nerve terminal populations identified by size,   electrophysiological properties and neuropeptide content. Brain Research 2004, 1024: 203-211.

Isoflurane   and propofol inhibit voltage-gated sodium channels in isolated rat   neurohypophysial nerve terminals. Molecular   Pharmacology 2003, 64:373-381.


课题:

  1.运动对创伤性脑损伤导致的幼龄大鼠皮层神经元损伤及运动功能缺陷影响的机制研究    国家体育总局

  2.创伤性脑损 导致幼龄小鼠皮层神经元进行伤的机制研究       省自然科学基金